WHO trials find Remdesivir ineffective in treating COVID-19

Aileen Cerrudo   •   October 16, 2020   •   313

Results of clinical trials showed that Remdesivir is ineffective in treating patients with COVID-19, according to the World Health Organization (WHO).

“Interim results from the Solidarity Therapeutics Trial, coordinated by the World Health Organization, indicate that REMDESIVIR, appeared to have little or no effect on 28-day mortality or the in-hospital course of COVID-19 among hospitalized patients,” according to the WHO report.

Remdesivir is initially a treatment for the ebola virus and there have been previous evidence that it may also be used in treating COVID-19.

The WHO said they will evaluate other treatment options for the solidarity trials in 500 hospital sites.

Due to this, the Department of Health (DOH) said they might halt administering the said drug in the Philippines.

“Kapag dumating tayo doon sa point na ang isang gamot ay matagpuan or makapagbigay ng ebidensya base doon sa mga nakukuha nating resulta sa mga pasyenteng binibigyan nito na hindi siya effective at tsaka nakakapagbigay siya ng more harm than good, puwedeng itigil ang mga gamot na iyan during the course of the trial,” Department of Health Undersecretary Maria Rosario Vergeire said.

The WHO had previously stopped the use of hydroxychloroquine and lopinavir/ritonavir last June and July after finding evidence that the drugs are ineffective in treating COVID-19 patients under solidarity trial in various countries.

Meanwhile, Vergeire said the WHO will use the chemotherapy drug acalabrutinib in their solidarity trial. She also added that the agency is currently exploring other anti-viral drugs in their trials.

“Dinagdag ng WHO iyong gamot na Alcalabrutinib this is a chemotherapeutic regimen na isa na po siya sa idadagdag natin sa treatment arm ng WHO solidarity trial, she said.

The DOH, will release on Monday (October 19) an update on the initial results of the solidarity trial conducted in the country as well as in other countries. AAC (with reports from Aiko Miguel)


FDA assures enough supply of medicines for COVID-19 patients

Robie de Guzman   •   March 29, 2021

MANILA, Philippines – The Food and Drug Administration (FDA) on Monday assured the public that there is enough supply of medicines used to treat patients with COVID-19.

FDA director-general Eric Domingo made the assurance following reports that the supply of medicines for the treatment of coronavirus infected patients is depleting.

During a Laging Handa virtual briefing, Domingo confirmed that some medications for COVID-19 patients are running low due to the recent surge of infections.

“On dexamethasone, we did not have problems there. For the other medicines, we had problems because there has been an increase in the number of patients, and the hospitals’ supplies were depleted,” he said.

“But we have issued a compassionate special permit for Remdesivir, and there will be deliveries for immediate use,” he added.

Domingo said suppliers have already assured that additional stocks are on hand and are expected to be delivered within this week.

He, however, said that the distribution of the medicines will be limited.

“Just this morning yung mga companies na nag-i-import ng Remdesivir per hospitals nagbigay sa amin ng report and most of them have stocks on hand. So makakapagdeliver naman po sila this week. Talaga naman pong ano lang ididistribute nila ng hindi maramihan sa lahat ng ospital para lahat eh unti-unti pong magamit ito sa mga nangangailangan,” Domingo said.

Manila LGU buys 2,000 remdesivir vials for COVID-19 patients

Aileen Cerrudo   •   August 13, 2020

The Manila City government has acquired 2,000 remdesivir vials to treat coronavirus disease (COVID-19) patients.

Manila Mayor Isko Moreno Domagoso on Thursday (August 13) announced that the local government spent P13 million to purchase the vials from Mylan, the pharmaceutical firm that created remdesivir.

The mayor said the initiative aims to strengthen the city’s efforts to provide better medical treatment for COVID-19 patients confined in Manila’s district hospitals.

“Kung saka-sakali kakailanganin pa, bibili pa po tayo, mapangalagaan lang namin kayo, mapataas lang namin ang probabilidad na kapag kayo ay na-infect ng COVID-19, kayo ay mag-recover,” Domagoso said.

Vice Mayor Honey Lacuna-Pangan also stressed that remdesivir will only be used in hospitals and added that the medication is not available over-the-counter.

“Sa ospital lang po ito ginagamit, hindi po ito sa bahay ginagamit, para po ito sa atin pong mga pasyente na mayroong mild, moderate or severe na mga sintomas,” Lacuna-Pangan said.

In a statement, the local government said the antiviral medication has been approved for use at the city’s six district hospitals by the Philippine Food and Drug Administration. AAC


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